FHA
Description
Hofmann & Bucher (1995): | The typical FHA domain comprises approximately 55-75 amino acids and contains three highly conserved blocks separated by more divergent spacer regions. |
PFAM: | The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes - DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples. |
References:
1) | Durocher, D; Jackson, SP. 2002. The FHA domain. FEBS Lett. 513(1):58-66 PubMed |
2) | Hofmann, K; Bucher, P. 1995. The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors. Trends Biochem. Sci. 20(9):347-9 PubMed |
Summary
Name: | FHA |
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Class: | TR |
Number of species containing the TAP: | 130 |
Number of available proteins: | 1969 |
The colour code corresponds to the rules for the domains:
should be contained
should not be contained
should not be contained
Domain rules:
(Domain names are clickable)
Phylogenetic tree for Archeaplastida:
No tree was calculated yet.
TAP distribution:
The following table shows the distribution of FHA over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.
Minimum | Maximum | Average | Median | Standard deviation |
---|---|---|---|---|
0 | 62 | 16.37 | 15 | 9.86 |