FHA

Description

Hofmann & Bucher (1995): The typical FHA domain comprises approximately 55-75 amino acids and contains three highly conserved blocks separated by more divergent spacer regions.

PFAM: The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes - DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples.

References:


1) Durocher, D; Jackson, SP. 2002. The FHA domain. FEBS Lett. 513(1):58-66 PubMed
2) Hofmann, K; Bucher, P. 1995. The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors. Trends Biochem. Sci. 20(9):347-9 PubMed


Summary

Name: FHA
Class: TR
Number of species containing the TAP: 130
Number of available proteins: 1969

The colour code corresponds to the rules for the domains:

should be contained
should not be contained

Domain rules:


(Domain names are clickable)


Phylogenetic tree for Archeaplastida:

No tree was calculated yet.



TAP distribution:

The following table shows the distribution of FHA over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.

Minimum Maximum Average Median Standard deviation
06216.37159.86

List of species containing FHA sorted by kingdomcladesupergrouporderfamily:

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expand kingdom Archaeplastida (2144 proteins in 130 species)
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A list of species letter codes included in the protein names can be found here (opens in new tab).


Impressum